She discovered and developed purified, specific active tumor-associated antigens (TAA). With T. Stewart, she was the first to do clinical tests of TAA vaccines in lung cancer patients. Using monoclonal antibodies, she prepared epitopes for a reverse enzyme immunoassay to predict the success of their immunotherapy. She and other workers in her lab continued to work on many types of cancer with a view to identifying TAAs and cooperating with oncologists experienced in a particular type of cancer.Wikipedia has an extended biography of Ariel in German. (Push the “Translate” button at the top of the page.) That page has links to a list of publications and to a few online research articles and so forth.
In September, 2013, during Alumni weekend at George Washington University, resident Ariel Hollinshead Hyun received an Alumni Achievement Award. The blog of the GW Alumni Association says that colleagues describe Ariel as the “Mother of Immunology.” In 1976, Ariel was named Medical Woman of the Year by the Joint Board of American Medical Colleges, and described as “one of the few women in our country who….will receive lasting distinction by applying the principles of basic research to the diseases of humanity.” The article in the GWAA website summarizes her work with the words:
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